Experimental Seizure Model Induced by Dibutyryl Derivatives of Cyclic Nucleotides
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چکیده
منابع مشابه
Human platelet secretion and aggregation induced by calcium ionophores. Inhibition by PGE1 and dibutyryl cyclic AMP
Ca2+, Mg2+-ionophores X537A and A23,187 (10(-7)-10(-6) M) induced the release of adenine nucleotides adenosine diphosphate (ADP, adenosine triphosphate (ATP), serotonin, beta-glucuronidase, Ca2+, and Mg2+ from washed human platelets. Enzymes present in the cytoplasm or mitochondria, and Zn2+ were not released. The rate of ATP and Ca2+ release measured by firefly lantern extract and murexide dye...
متن کاملHuman Platelet Secretion and Aggregation Induced by Calcium Ionophores Inhibition by PGE and Dibutyryl Cyclic AMP
Ca 2+, Mg2+-ionophores X537A and A23,187 (10-r-10 -6 M) induced the release of adenine nucleotides adenosine diphosphate (ADP, adenosine triphosphate (ATP), serotonin, /3-glucuronidase, Ca 2+, and Mg 2+ from washed human platelets. Enzymes present in the cytoplasm or mitochondria, and Zn 2+ were not released. The rate of ATP and Ca 2+ release measured by firefly lantern extract and murexide dye...
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The human promyelocytic leukemia cell line HL-60 is induced to differentiate along a myelocytic pathway by dibutyryl cyclic adenosine monophosphate (dbcAMP). Other cAMP analogs are ineffective as inducing agents. The effect of these compounds on expression of c-myc was investigated using a DNA probe for c-myc to detect RNA transcripts. The dose response and time to commitment for reduction in c...
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Both exposure to cold and administration of aminophylline result in rapid increases in cyclic adenosine monophosphate (cyclic AMP) in the adrenal medulla and adrenal cortex. These increases are followed by dramatic increases in ornithine decarboxylase activity is due to new enzyme systhesis. The data suggest that the decarboxylase activity is regulated by an increase in cyclic AMP.
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In a previous communication, we showed that beta-adrenergic stimulation of cardiac muscles was associated with an increase in the rate of cycling of crossbridges as measured by perturbation analysis in the frequency domain. In this analysis, the frequency at which dynamic stiffness is a minimum (fmin) is taken as a measure of the rate of crossbridge cycling. In this paper, we test the hypothesi...
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ژورنال
عنوان ژورنال: Journal of the Japan Epilepsy Society
سال: 1983
ISSN: 0912-0890,1347-5509
DOI: 10.3805/jjes.1.88